Psilocybin Adventures

I found this on the SAMHSA (Substance Abuse and Mental Health Services Administration) website. Keep in mind that LSD is a similar molecule to psilocybin and psilocin and may have similar detection properties. The elimination half-life of LSD is 3.6 hours and the elimination half-life of psilocybin and psilocin is ~3 hours.

It is also important that none of the mentioned molecules are eliminated in the kidneys, but instead are eliminated in the liver, minimizing the elimination of metabolites via urine.

Quoted from SAMHSA:

ā€œLSD: Very little of the parent drug, LSD, is excreted in urine and it can be detected for only approximately 4 hours. The most abundant metabolite is nor-LSD (N-desmethyl-LSD), which is generally detected at a cutoff level of 0.5 ng/mL. Confirmatory testing is usually done with LC/MS or LC/MS/MS.ā€

Good point for non-government related businesses, but business that have government contracts or DOT regulated employment do not have that choice in the tests administered. They must conform to government requirements.

I asked an addiction doctor I know and he stated that employers who do drug test generally run a 12 panel test. He said that he couldn’t comment on government requirements.

That said, the SAMHSA recommendation for DOT tests includes the following. I would expect that the requirement for government employees or government contractors are similar.

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I always heard, but have never confirmed, that the only way to test for LSD was by performing a spinal tap. Again, this was when i was back in college so take it with a grain of salt as for the truthfulness of this statement. Thank you for posting more information on this subject.

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Wonderful article. Well now i know. Thanks again.

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Hair follicle test also

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Drug test trivia (as applicable to urine testing):

THC also has a short half-life (~2.5 days); however, because THC is fat soluble it is stored in your fat cells and has a 4 to 6 week detection time depending on your metabolic rate. Psilocybin is water soluble and can thus clear your system quickly.

Cocaine is an interesting case too. The drug test isn’t actually for cocaine. The test is for a cocaine metabolite called benzoylecgonine. The only way benzoylecgonine can get in your system is by ingesting cocaine. I’m not suggesting that any of us use cocaine or really care, but the point is that drugs are sometimes not tested for directly, which is important. Some drug testing is not for the drug itself, but for the metabolites that the body makes as a result of a drug’s use.

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Very interesting. I do appreciate the info. Oh! For what its worth, i hate cocaine. Too much of a roller coaster for me. :rofl:

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Wow! Thats some really good stuff in that video. I love education as i also have two BS degrees in this field. Love the info, keep it coming… :v::blush:

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Huberman generally posts clips from upcoming episodes. I expect Huberman will publish the full episode (~90 minutes or so) in the coming weeks. I’ll post the full episode when he does.

Huberman puts out a ton of good stuff. It’s a good subscribe on YouTube if you like his content and approach.

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Have you tried this ā€œeye maskā€ experience and if so what were your conclusions of such?

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I only microdose. I haven’t tripped since college when I did an LSD journey.

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Score!

I ordered 4 B+ syringes. The shipping email said that they were throwing in a free PES Hawaiian cubensis syringe, but all of the labels say B+, so I have 5 B+. I’m fine with that.

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Funny story. The only thing I still remember about this trip is being the the bathroom of some guy’s apartment where we were partying and watching a toilet paper roll liquefy and melt down the wall. It was 43 years ago and I still remember it. It was absolutely bizarre.

I have overcooked a microdose a few times and had some interesting experiences.

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Hey I’m sorry I did not see your post about how much cc I used to innoculate.

Roughly around 2ccs each jar.

The 3 jars that are growing mycelium have doubled in size seem to be growing at a good rate just an update.
Also I can’t wait to see your fruiting on this run I hope you get that big supply of them! Your pictures look awesome!

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Happy to see it. I figured that they would eventually take off.

You are in quart jars, right? I use 3 cc for pint jars. It’s a balance. Too little ccs and colonization will be slower than it could be. Too much and the liquid will collect at the bottom of the jar. Wet grain will not colonize. This happened with my most recent set of jars. Not because I put too many ccs in, but because I didn’t let the grain dry sufficiently after I cooked it. The result regarding too much moisture at the bottom of the jar is the same. You can see the outcome in the following pic.

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That might be my problem then I have quart jars and I used only 2ccs some of them maybe even less. My grain could be too wet also on some of the jars. I’ll know better next time. Even if I only get 3 jars I’ll still be happy. I still have 2 syringes left I was going to make some liquid culture too in the future try my hand at that.

Your jars still look really good though some strong mycelium. Thanks for your help!

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I think that it was you who asked for a LC tutorial.

I do mine in half pint jars. Fill the jars only half to 2/3 full with RO or distilled. Don’t fill them all the way up or they will boil over when pressure cooked. Mycelium needs a sugar or some other starch to feed on as it develops. People use all kinds of thing for the sugar. Some use extra light malt extract, for instance. I use Karo syrup - 1/2 teaspoon per jar. Whatever you use the sugar content should be ~5%. Too much sugar and mycelium won’t grow and too little and the mycelium will starve. Once I add the Karo I put a lid on the jar loosely. I use plastic lids with a 1/4 hole drilled in them and cover the hole with micropore tape. I then PC the jars for 30 minutes to sterilize them. Once the 30 minutes are up, leave the jars and let the pressure cooker sit and relieve the pressure on its own. They need the pressure while the jars cool down to prevent them from boiling over. Relieving the pressure while they are hot will cause the jars to boil over. Once the jars are cooled I’ll poke a needle through the micropore tape and put in 1 ml of spores. Cover the compromised tape with another piece of tape once the inoculation is done. It will then take a few weeks for some nice mycelium to develop in the jars. I store my colonizing jars in a Martha tent where I can control the temp in the high 70s F.

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Saweeet yes perfect! Nice write up too thank you! So I can use distilled water?

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