@AAA, For the cancer treatment, suggested daily dose is 1 gram of cannabis oil per day for 60 days (or until cure) . However, 1 gram of Cannabis Oil is huge amount to take even for the person who used to marijuana. My husband never had marijuana before and in order to build up tolerance, he will have to take very small amount daily and increase to 1 gram.
However, he didn’t have the luxury of the time. He was already going down hill really fast at the time, Also, he was, still is, working full time and he can’t function with high dose of THC.
The reason for the suppository method (people calls Backdoor method) is to by-pass the liver. The liver is the reason we get high. When we take RSO orally, THC travels through the liver to the brain to induce a head high. Also, when we smoke, it travels through the lungs to the villi, then on to the liver. Also, taking marijuana orally or smoking, both method takes the longest because of the digestive process and the amount of travel it takes to get to the brain. In the brain, THC interacts with nerve receptors, causing euphoria. When RSO administered rectally, the oil directly enters the bloodstream through the cell walls and goes directly into the body, which is quickly distributed through the vascular system.
So, administering RSO rectally is a direct application to the bloodstream, bypassing the liver. Cannabis suppositories allow for larger doses of medicine without the head high versus smoking and ingesting orally.
However, even with the backdoor method, you can not go deeper than 1-1/2 inches . If you do, the oil will go thru Liver and you’ll get high just like you would ingest. So, the key is to put oil just deep enough to hit between external anal sphincter and internal anal sphincter. (which is located about 1-1/2 from the entry point). *** This is so important. I didn’t know about hitting the between external anal sphincter and internal anal sphincter and first 3 days oil went up as far as the syringe allowed and he was out cold for 5 days.
I prepare RSO in 1 gram syringes ahead of the time, so he can just grab 1 syringe daily without worry about measuring, etc. I also use syringe with luer slip tip, not luer lock tip.
On the side note: According to my research, Cannabis suppositories deliver around 80 percent of the plant medicine, while taking cannabis orally delivers around 35 percent and smoking around 15 percent. So, rectal delivery of cannabis, provides the maximum amount of oil delivered with zero head high and no known side-effects.
I hope this answers your question.