What is the cause of this leaf problem?

You need to fill out this support ticket it will help everyone to help you.

http://ilgmforum.com/t/fill-out-a-support-ticket/1458/17

But to help / you out till the then. It looks to be nutrient burn.
The soil you are using did or does it have nutrients in it?
And 2nd. Have you been feeding your plants nutrients?
Because if you have I’ll bet Your PH is way out of range.
If you have…stop feeding and water only! And if you don’t have a PH meter go here. You need to have one.

Hope this helps

B Safe
Will